HYALURONIC ACID-CURCUMIN NANOPARTICLES FOR PREVENTING THE PROGRESSION OF EXPERIMENTAL AUTOIMMUNE UVEITIS THROUGH THE KEAP1/NRF2/HO-1 SIGNALING PATHWAY

Abstract Globally, uveitis is a collection of intraocular inflammatory disorders that affect mainly the uvea, resulting in irreversible blindness and a heavy socioeconomic burden.Excessive autoimmune inflammation and oxidative stress are major drivers that contribute to the initiation and progression of uveitis.Nevertheless, current therapeutic met

(1) Background: Since the advent of zidovudine in 1987, antiretroviral therapy has undergone significant evolution, marked by the introduction of 34 antiretroviral drugs and 24 fixed-dose combinations.Despite these advances, hepatotoxicity remains a formidable challenge, influencing morbidity, mortality, and treatment adherence in HIV-infected pati

Scandinavian design as a style, within the filed of furniture history and interior, emerges and develops in the aftermath of World War II in Central Europe, to be retained later in the Nordic countries: Sweden, Denmark and Norway.The Scandinavian modern style is mainly characterized by wood furniture with bright shades, pronounced lines, forms and

Energy intensity is one of the most important energy feature that has a dramatic value in energy system of Iran.Indeed, Iran is one of the most energy intensive countries in the world and its main reason is related to high energy consumption in Wheel Axle household section.In this article, we present a non-linear model that considers three scenario